Spudich Lab: Current Publications

224. Tang, S, Liao, J. C, Dunn, A.R., Altman, R.B., Spudich, J. A. and Schmidt, J. P. (2007). Predicting Allosteric Communication in Myosin via a Pathway of Conserved Residues. J Mol Biol 373: 1361-1373. (Full PDF Text Available.)

223. Altman, D., Goswami, D., Hasson, T., Spudich, J. A. and Mayor, S. (2007). Precise Positioning of Myosin VI on Endocytic Vesicles In Vivo. PLos Biol. 5(8): e-published ahead of print. (Full PDF Text Available.)

222. Geething, N. C. and Spudich, J. A. (2007). Identification of a minimal myosin Va binding site within an intrinsically unstructured domain of melanophilin. J Biol Chem 282(29): 21518-2158. ( Full PDF Text Available.)

221. Liao, J. C., Spudich, J. A., Parker, D. and Delp, S. (2007). Extending the absorbing boundary method to fit dwell-time distributions of molecular motors with complex kinetic pathways. PNAS 104 (9): 3171-3176. (Full PDF Text Available.)

220. Dunn, A. R. and Spudich, J. A. (2007). Dynamics of the unbound head during myosin V processive translocation. Nat Struct Mol Biol. 14 (3): 246-248. (Full PDF Text Available.)

219. Bryant, Z., Altman, D. and Spudich, J. A. (2007). The power stroke of myosin VI and the basis of reverse directionality. PNAS 104 (3): 772-777. (Full PDF Text Available)

218. Dean, S. O. and Spudich, J. A. (2006). Rho Kinase's Role in Myosin Recruitment to the Equatorial Cortex of Mitotic Drosophila S2 Cells Is for Myosin Regulatory Light Chain Phosphorylation. PLoSOne 1(1): e131. (Full PDF text available).

217. Churchman, L. S., Flyvbjerg, H. and Spudich, J.A. (2006). A Non-Gaussian Distribution Quantifies Distances Measured with Fluorescence Localization Techniques. Biophysical Journal 90: 668-671. (Full PDF Text Available)

216. Purcell, T. J., Sweeney, H. L. and Spudich, J. A. (2005). A force-dependent state controls the coordination of processive myosin V. Proc. Natl. Acad. Sci. USA 102 (39): 13873-13878. (Full PDF Text Available)

215. Dean, S.O., Rogers, S.L., Stuurman, N., Vale, R.D. and Spudich, J.A. (2005). Distinct pathways control recruitment and maintenance of myosin II at the cleavage furrow during cytokinesis. Proc. Natl. Acad. Sci. USA 102: 13473-13478. (Full PDF Text Available)

214. Rock, Ronald S., Ramamurthy, Bhagavathi, Dunn, Alexander R., Beccafico, Sara, Rami, Bhaadresh R., Morris, Carl, Spink, Benjamin J., Franzini-Armstrong, Clara, Spudich, James A. and Sweeney, H. Lee (2005) A Flexible Domain Is Essential for the Large Step Size and Processivity of Myosin VI. Molecular Cell 17: 603-609 (Full PDF Text Available)

213. Churchman, L. Stirling, Ökten, Zeynep, Rock, Ronald S., Dawson, John F. and Spudich, James A. (2005) Single molecule high-resolution colocalization of Cy3 and Cy5 attached to macromolecules measures intramolecular distances through time. Proc. Natl. Acad. Sci. USA 102 (5): 1419-1423. (Full PDF Text Available)

212. Lakshmikanth, GS, Warrick, HM and Spudich, JA. (2004) A mitotic kinesin-like protein required for normal karyokinesis, myosin localization to the furrow, and cytokinesis in Dictyostelium. Proc. Natl. Acad. Sci. USA 101 (47): 16519-16524 (Full PDF Text Available)

211. Hostetter, Daniel, Rice, Sarah, Dean, Sara, Altman, David, McMahon, Peggy M., Sutton, Shirley, Tripathy, Ashutosh and Spudich, James A. (2004) Dictyostelium Myosin Bipolar Thick Filament Formation: Importance of Charge and Specific Domains of the Myosin Rod. PLoS Biology 2 (11). (Full PDF Text Available)

210. Ökten, Zeynep, Churchman, L. Stirling, Rock, Ronald S. and Spudich, James A. (2004) Myosin VI walks hand-over-hand along actin. Nature Structural and Molecular Biology 11 (9): 884-887 (Full PDF Text Available)

209. Altman, D. A., Sweeney, H. L. and Spudich, J. A. (2004) The Mechanism of Myosin VI Translocation and Its Load-Induced Anchoring. Cell 116: 737-749 (Full PDF Text Available)

208. Robinson, D. N. and Spudich, J. A. (2004) Mechanics and Regulations of Cytokinesis. Current Opinion in Cell Biology 16: 1-7. (Full PDF Text Available)

207. Rock, R. S., Purcell, T. J. and Spudich, J. A. (2003) Mechanics of Unconventional Myosins. The Enzymes XXIII: 55-85.

206. Rice, S. E., Purcell, T. J. and Spudich, J. A. (2003) Building and Using Optical Traps to Study Properties of Molecular Motors. Methods Enzymol. 361: 112-133. (Full PDF Text Available)

205. Dawson, J. F., Sablin, E. P., Spudich, J. A., and Fletterick, R. J. (2003) Structure of an F-actin Trimer Disrupted by Gelsolin and Implications for the Mechanism of Severing. J. Biol. Chem. 278 (2): 1229-1238. (Full PDF Text Available)

204. Spudich, J. A. (2002) Quatitative Measurements of Myosin Movement In Vitro: The Reductionist Approach Carried to Single Molecules. In Molecular Motors, M. Schliwa, editor. Wiley-VCH, pp 271-286.

203. Purcell, T. J., Morris, C., Spudich, J. A., and Sweeney, H. L. (2002) Role of the lever arm in the progressive stepping of myosin V. Proc. Natl. Acad. Sci. USA 22: 14159-141-64. (Full PDF Text Available)

202. Sablin, E. P., Dawson, J. F., VanLoock, M. S., Spudich, J. A. and Egelman, E. H. (2002) How does ATP hydrolysis control actin's associations? Proc. Natl. Acad. Sci. USA 99 (17): 10945-10947. (Full PDF Text Available)

201. Liang, W, Licate, L. S., Warrick, H. M., Spudich, J. A., and Egelhoff, T. T. (2002) Differential localization in cells of myosin II heavy chain kinases during cytokinesis and polarized migration. BMC Cell Bio. 3 (1):19-34. (Full PDF Text Available)

Publications (2002 - Present)